Differential Ability of Surface and Endosomal TLRs To Induce CD8 T Cell Responses In Vivo
نویسندگان
چکیده
منابع مشابه
Differential ability of surface and endosomal TLRs to induce CD8 T cell responses in vivo.
TLR activation on dendritic cells (DCs) induces DC maturation and secretion of proinflammatory cytokines, both of which are important for activation and differentiation of CD4 T cells. The importance of TLR activation on DCs for CD8 T cell responses is less clear. In this study, we tested the ability of different TLRs to regulate CD8 T cell responses to pathogens. We found that although all TLR...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2014
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.1302244